A kinase with keen eyes

A keen eye for risk.

A 56 year old woman was referred to the rapid access chest pain clinic with stable angina pectoris. Her only cardiovascular risk factor was a family history of atherosclerosis, with her mother suffering from myocardial infarction at 50. Her body mass index was 20 kg/m and the main abnormality on examination was the eye sign shown in . Fasting serum cholesterol and low density lipoprotein were b...

Commentary on 'What is the point: will screening mammography save my life?' by Keen and Keen

Commentary on Keen and Keen 'What is the point: will screening mammography save my life?' BMC Medical Informatics and Decision Making, 2009.

Industry toxicologists keen on reducing animal use.

A child with swelling between the eyes.

A 10-year-old girl presented with a one-week history of swelling over her nasal bridge. The swelling began with a small pea-sized lesion that gradually increased in size over the one-week period. It was associated with throbbing pain and intermittent low-grade fever. Visual field and examination of extraocular muscle movement were normal. Although she was examined by a general practitioner and ...

FMS-like Tyrosine Kinase-3 Mutation in a Child with Standard-risk ALL and Normal Karyotype

FMS-like tyrosine kinase-3 is a receptor tyrosine kinase expressed by immature hematopoietic cells and is important for the normal development of stem cells and the immune system. Mutations of FMS-like tyrosine kinase-3 have been detected in about 30% of patients with acute myelogenous leukemia and a small number of patients with acute lymphoblastic leukemia. The FMS-like tyrosine kinase-3 muta...